Coming off a bye, the rested Tennessee Titans will return home to take on their division rival Indianapolis Colts on Sunday at Nissan Stadium.
The Titans (1-3) are returning after a 31-12 victory over the Miami Dolphins in their last outing to close Week 4. The Colts (2-3) are coming off a disappointing 37-34 loss to the Jacksonville Jaguars in Week 5 action.
Heading into Week 6, both Titans starting quarterbacks — Will Levis (shoulder) and Colts Anthony Richardson (oblique) — are battling injuries. Head coach Brian Callahan was optimistic that Levis would be available for this match-up, but Richardson is more of a question mark.
There is a touch of uncertainty in what could be a battle between veteran backup quarterbacks Mason Rudolph and Joe Flacco. Rudolph looked good and was a solid game manager in relief of Levis in Week 4. However, Flacco has looked tremendous in 2024 and the oddsmakers gave the Colts a slight edge.
The Titans open the week as 1-point home underdogs against the Colts in what is an important game for both teams, per BetMGM. The over/under is 42.5 points, and the money line is -110.
The Titans should be rested coming off their bye and the staff has had an extra week to prepare, which should be a benefit as they attempt to build upon their first win. Everyone will see how this plays out on Sunday when the teams take the field in Nashville.