The Titans defensive line took a larger hit than expected today when it was announced that the team was placing second-year nose tackle T’Vondre Sweat on injured reserve. He’ll now be forced to miss Tennessee’s next four games, at least. 
A second-round pick out of Texas last year, Sweat was an impressive rookie, stepping in to start every game but one in his first year of NFL play. Among full-time starters on the defense, Sweat graded out as the team’s second-best defender, according to Pro Football Focus (subscription required), behind only his neighbor on the line, Jeffery Simmons.
Sweat had missed the Titans’ Week 2 matchup with an ankle injury but had been working his way back onto the field this week. Per NFL writer Paul Kuharsky, Sweat reinjured his ankle on Thursday, throwing his recovery progress off track. The severity of his ankle injury is unclear at the moment, but Tennessee placing him on IR indicates that it will take at least four weeks for Sweat to recover.
To help fill out the defensive line a bit, the Titans are calling up defensive tackle Carlos Watkins as a standard gameday practice squad elevation. Joining Watkins in that regard will be linebacker Kyzir White.
Practice squad offensive tackle John Ojukwu will also be active for Sunday’s game but as a member of the 53-man roster. With right tackle JC Latham set to miss his second straight game with a hip injury, Ojukwu will continue to fill in as the starter on that side. While Latham not being placed on IR indicates he may not be out for four weeks, signing Ojukwu to the active roster helps the Titans avoid the three-time elevation limit on a single practice squad contract, meaning they likely intend to utilize Ojukwu for more than just three games.