The Tennessee Titans (3-11) will visit the Indianapolis Colts (6-8) at Lucas Oil Stadium in Indianapolis, Indiana on Sunday afternoon.
Opening the week, the Titans were listed as 4.5-point road underdogs but that spread has softened slightly with Tennessee at +3.5 as of this writing.
Let’s take a look at who some of the experts and insiders around the league are taking in the Week 16 matchup:
| Expert | Pick | Score (if applicable) |
| Dan Graziano (ESPN) | Colts | N/A |
| Matt Bowen (ESPN) | Colts | N/A |
| Seth Wickersham (ESPN) | Colts | N/A |
| Pete Prisco (CBS) | Colts | 24-17 |
| John Breech (CBS) | Colts | 19-16 |
| Jordan Dajani (CBS) | Colts | 24-20 |
| Nate Davis (USA TODAY) | Colts | 24-16 |
| Lorenzo Reyes (USA TODAY) | Colts | 17-16 |
| Bill Bender (Sporting News) | Colts | 21-18 |
| Vinnie Iyer (Sporting News) | Colts | 24-17 |
The Titans once again get the unanimous shun with all 10 members of the above panel picking against them this week. However, if there is a silver lining to be found it’s that available score predictions suggest this will be a close one.
Other experts and analysts from around the league are equally bullish on the Colts with 90 percent picking them to win, per NFL Pickwatch.
Fans are notably more pessimistic with just five percent predicting a Titans upset victory.